E-mail: hassanyola yahoo. Hereditary spherocytosis HS is a familial hemolytic disorder with marked heterogeneity of clinical features, ranging from an asymptomatic condition to a fulminant hemolytic anemia. Although a positive family history of spherocytosis increases the risk for this disorder, it may be sporadic in some cases.
In severe cases the disorder may be detected in early childhood, but in mild cases it may go unnoticed until later in adult life. A year-old Nigerian woman presented with mild anemia, jaundice, splenomegaly and a history of multiple blood transfusion.
She was managed discuasion on nutritional supplements and a significant regression of symptoms after 6 months was achieved. Hereditary spherocytosis HS is a rare Site Mount Isa discussion pour adulte red blood cell membrane disorder that is characterized by spherically shaped red blood corpuscles on peripheral blood smear.
This case is reported in view of the rarity of this disorder coupled with the few specialists Haematologist to diagnose plur manage such a disorder in our environment. It is hoped that this report Granville good massage bring increase awareness on the existence of HS in our Iwa and hence an increase index of suspicion and prompt referral to avoid unnecessary use of blood transfusion.
A year-old Brisbane homly girls presented with recurrent abdominal swelling, stunted growth relatively to her siblings and age discussoon. She has had four units of blood transfusion in childhood; her last transfusion was 10 years prior to presentation.
She also has recurrent yellowish discoloration of the eyes. No family history of sickle cell disease. Examination revealed a young lady, with a small and short stature, mildly pale, moderately jaundiced and has a gnathopathy. The spleen was enlarged by 6cm below the right costal margin but the liver was not palpably enlarged. Laboratory investigation shows Sife haematocrit of 0. The white cell and platelets are of normal morphology. Her genotype was AA.
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A family study could not be carried in this case since her family resides in the Eastern part of the country. After six months, her clinical state improved with jaundice decreasing to just a tinge, the spleen regressed to 2cm while the packed cell volume increased to 0.
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